Claritop (Clarithromycin) is a semi-synthetic derivative of Erythromycin A. It exerts its anti-bacterial action by binding to the 50s ribosomal sub-unit of susceptible bacteria and suppresses protein synthesis. It is highly potent against a wide variety of aerobic and anaerobic gram-positive and gram negative organisms. The minimum inhibitory concentrations (MICs) of Clarithromycin are generally two-fold lower than the MICs of Erythromycin. The 14-hydroxy metabolite of clarithromycin also has anti-microbial activity. The MICs of this metabolite are equal or two-fold higher than the MICs of the parent compound, except for H.influenza where the 14-hydroxy metabolite is two-fold more active than the parent compound.
Claritop –250mg Film Coated Tablets: Each F/C tablet contains 250mg Clarithromycin in blisters pack of 14 tablets.
Claritop –500mg film coated tablets: Each F/C tablet contains 500mg Clarithromycin in blister packs of 20, 14 tablets.
Claritop Suspension: Each 5 ml contains 125mg Clarithromycin in 60& 100ml bottle.